Estimate Marginal distribution and Gaussian Copula for Gene Expression Matrix
Source:R/ExprSimulator.R
Est_ModelPara.Rd
Estimate Marginal distribution and Gaussian Copula for Gene Expression Matrix
Usage
Est_ModelPara(
expr,
anno,
sim_method = c("ind", "copula"),
region = NULL,
ncores = 1,
subsetN = NULL
)
Arguments
- expr
Expression levels of input data
- anno
Cell type annotation of input data
- sim_method
c('ind', 'copula')
- region
description
- ncores
No of cores for parallel computing.
- subsetN
If the number of cells is large, one can use it to estimate expression distribuitons from subset of cells (e.g. subsetN=2500) per cell type.