This function uses input parameters to simulate expression for all regions.
Usage
Use_scDesign2(
ppp.obj,
model_params,
expr,
region = NULLL,
depth_simu_ref_ratio = 1,
sim_method = c("copula", "ind"),
region_specific_model = NULL,
seed
)Arguments
- ppp.obj
Cells as points on a spatial map for all regions.
- model_params
Provide model parameters including marginal distributions and copula (if not NULL).
- expr
Gene expression (count) in reference data.
- region
Cell regions in reference data.
- depth_simu_ref_ratio
Relative sequencing depth in comparison of reference data.
- sim_method
Simulate independent genes using'ind' or correlated genes using 'copula'.
- region_specific_model
Whether estimation model differ in different regions.
- seed
Seed